منابع مشابه
Novel targeted therapies for mantle cell lymphoma
Mantle cell lymphoma (MCL) is an aggressive B-cell malignancy characterized by short median survival despite intensive therapies. The clinical behavior of MCL may be due to the complex pathophysiology of the disease which includes its genetic hallmark, the chromosomal translocation t(11;14) resulting in aberrant expression of cyclin D1, alteration in the DNA damage response, and constitutive ac...
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Kazuo Okamoto1,2,3) and Hiroshi Takayanagi *,1,2,3,4) 1)Department of Cell Signaling, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan 2)Global Center of Excellence (GCOE) Program, International Research Center for Molecular Science in Tooth and Bone Diseases, Tokyo, Japan 3)Japan Science and Technology Agency (JST), ERATO, Takayanagi Osteonetwor...
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ژورنال
عنوان ژورنال: Current Opinion in Immunology
سال: 2009
ISSN: 0952-7915
DOI: 10.1016/j.coi.2009.09.008